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| Competence (biology) ： ウィキペディア英語版 |
Natural competence
In microbiology, genetics, cell biology, and molecular biology, competence is the ability of a cell to take up extracellular ("naked") DNA from its environment. Competence may be differentiated between ''natural competence'', a genetically specified ability of bacteria which is thought to occur under natural conditions as well as in the laboratory, and ''induced'' or ''artificial competence'', which arises when cells in laboratory cultures are treated to make them transiently permeable to DNA. This article primarily deals with natural competence in bacteria, although information about artificial competence is also provided.
==History==
Natural competence was discovered by Frederick Griffith in 1928, when he showed that a preparation of killed cells of a pathogenic bacterium contained something that could transform related non-pathogenic cells into the pathogenic type. In 1944 Oswald Avery, Colin MacLeod, and Maclyn McCarty demonstrated that this 'transforming factor' was pure DNA. This was the first compelling evidence that DNA carries the genetic information of the cell.
Since then, natural competence has been studied in a number of different bacteria, particularly ''Bacillus subtilis'', ''Streptococcus pneumoniae'' (Griffith's "pneumococcus"), ''Neisseria gonorrhoeae'' and ''Haemophilus influenzae''. Areas of active research include the mechanisms of DNA transport, the regulation of competence in different bacteria, and the evolutionary function of competence.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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